Natural anti-CCR5 antibodies in HIV-infection and -exposure
نویسندگان
چکیده
منابع مشابه
CCR5 Mimicry by Sulfated Human Anti-HIV-1 Antibodies
HIV-1 envelope glycoprotein interaction with a principal coreceptor, CCR5, requires sulfated tyrosines on the CCR5 amino terminus. In this issue of Cell, Choe et al. identified tyrosine-sulfated, neutralizing antibodies against HIV-1 that apparently mimic CCR5. The results demonstrate for the first time that a natural posttranslational modification of an antibody can contribute substantially to...
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ژورنال
عنوان ژورنال: Journal of Translational Medicine
سال: 2011
ISSN: 1479-5876
DOI: 10.1186/1479-5876-9-s1-s4